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The Role of MMP7 and Its Cross-Talk with the FAS/FASL System during the Acquisition of Chemoresistance to Oxaliplatin

BACKGROUND: The efficacy of oxaliplatin in cancer chemotherapy is limited by the development of drug resistance. MMP7 has been related to the loss of tumor cell response to cytotoxic agents although the exact mechanism is not fully understood. Moreover, MMP7 is an independent prognosis factor for su...

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Detalles Bibliográficos
Autores principales: Almendro, Vanessa, Ametller, Elisabet, García-Recio, Susana, Collazo, Olga, Casas, Ignasi, Augé, Josep M., Maurel, Joan, Gascón, Pedro
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648894/
https://www.ncbi.nlm.nih.gov/pubmed/19266094
http://dx.doi.org/10.1371/journal.pone.0004728