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Statistical independence of the colocalized association signals for type 1 diabetes and RPS26 gene expression on chromosome 12q13
Following the recent success of genome-wide association studies in uncovering disease-associated genetic variants, the next challenge is to understand how these variants affect downstream pathways. The most proximal trait to a disease-associated variant, most commonly a single nucleotide polymorphis...
Autores principales: | Plagnol, Vincent, Smyth, Deborah J., Todd, John A., Clayton, David G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648905/ https://www.ncbi.nlm.nih.gov/pubmed/19039033 http://dx.doi.org/10.1093/biostatistics/kxn039 |
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