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Prostaglandin E2-EP1 and EP2 receptor signaling promotes apical junctional complex disassembly of Caco-2 human colorectal cancer cells

BACKGROUND: The apical junctional complex (AJC) is a dynamic structure responsible to maintain epithelial cell-cell adhesions and it plays important functions such as, polarity, mechanical integrity, and cell signaling. Alteration of this complex during pathological events leads to an impaired epith...

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Detalles Bibliográficos
Autores principales: Tanaka, Marcelo N, Diaz, Bruno L, de Souza, Wanderley, Morgado-Diaz, Jose A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648958/
https://www.ncbi.nlm.nih.gov/pubmed/19055708
http://dx.doi.org/10.1186/1471-2121-9-63