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Computationally Driven, Quantitative Experiments Discover Genes Required for Mitochondrial Biogenesis

Mitochondria are central to many cellular processes including respiration, ion homeostasis, and apoptosis. Using computational predictions combined with traditional quantitative experiments, we have identified 100 proteins whose deficiency alters mitochondrial biogenesis and inheritance in Saccharom...

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Detalles Bibliográficos
Autores principales: Hess, David C., Myers, Chad L., Huttenhower, Curtis, Hibbs, Matthew A., Hayes, Alicia P., Paw, Jadine, Clore, John J., Mendoza, Rosa M., Luis, Bryan San, Nislow, Corey, Giaever, Guri, Costanzo, Michael, Troyanskaya, Olga G., Caudy, Amy A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648979/
https://www.ncbi.nlm.nih.gov/pubmed/19300474
http://dx.doi.org/10.1371/journal.pgen.1000407