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Computationally Driven, Quantitative Experiments Discover Genes Required for Mitochondrial Biogenesis
Mitochondria are central to many cellular processes including respiration, ion homeostasis, and apoptosis. Using computational predictions combined with traditional quantitative experiments, we have identified 100 proteins whose deficiency alters mitochondrial biogenesis and inheritance in Saccharom...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648979/ https://www.ncbi.nlm.nih.gov/pubmed/19300474 http://dx.doi.org/10.1371/journal.pgen.1000407 |