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Evaluation of gene amplification and protein expression of HER-2/neu in esophageal squamous cell carcinoma using Fluorescence in situ Hybridization (FISH) and immunohistochemistry

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is the sixth most frequent neoplasia in Brazil. It is usually associated with a poor prognosis because it is often at an advanced stage when diagnosed and there is a high frequency of lymph node metastases. It is important to know what prognostic...

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Detalles Bibliográficos
Autores principales: Sato-Kuwabara, Yukie, Neves, José I, Fregnani, José HTG, Sallum, Rubens A, Soares, Fernando A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648997/
https://www.ncbi.nlm.nih.gov/pubmed/19128465
http://dx.doi.org/10.1186/1471-2407-9-6