Impact of genotyping errors on the type I error rate and the power of haplotype-based association methods

BACKGROUND: We investigated the influence of genotyping errors on the type I error rate and empirical power of two haplotype based association methods applied to candidate regions. We compared the performance of the Mantel Statistic Using Haplotype Sharing and the haplotype frequency based score tes...

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Detalles Bibliográficos
Autores principales: Marquard, Vivien, Beckmann, Lars, Heid, Iris M, Lamina, Claudia, Chang-Claude, Jenny
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648998/
https://www.ncbi.nlm.nih.gov/pubmed/19178712
http://dx.doi.org/10.1186/1471-2156-10-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648998/
https://www.ncbi.nlm.nih.gov/pubmed/19178712
http://dx.doi.org/10.1186/1471-2156-10-3

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