Telomere elongation involves intra-molecular DNA replication in cells utilizing alternative lengthening of telomeres

Alternative lengthening of telomeres (ALT) is a telomere length maintenance mechanism based on recombination, where telomeres use other telomeric DNA as a template for DNA synthesis. About 10% of all human tumors depend on ALT for their continued growth, and understanding its molecular details is cr...

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Detalles Bibliográficos
Autores principales: Muntoni, Alessandra, Neumann, Axel A., Hills, Mark, Reddel, Roger R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649016/
https://www.ncbi.nlm.nih.gov/pubmed/19095716
http://dx.doi.org/10.1093/hmg/ddn436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649016/
https://www.ncbi.nlm.nih.gov/pubmed/19095716
http://dx.doi.org/10.1093/hmg/ddn436

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