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Telomere elongation involves intra-molecular DNA replication in cells utilizing alternative lengthening of telomeres
Alternative lengthening of telomeres (ALT) is a telomere length maintenance mechanism based on recombination, where telomeres use other telomeric DNA as a template for DNA synthesis. About 10% of all human tumors depend on ALT for their continued growth, and understanding its molecular details is cr...
Autores principales: | Muntoni, Alessandra, Neumann, Axel A., Hills, Mark, Reddel, Roger R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649016/ https://www.ncbi.nlm.nih.gov/pubmed/19095716 http://dx.doi.org/10.1093/hmg/ddn436 |
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