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Human endogenous retrovirus HERV-K(HML-2) encodes a stable signal peptide with biological properties distinct from Rec

BACKGROUND: The human endogenous retrovirus HERV-K(HML-2) family is associated with testicular germ cell tumors (GCT). Various HML-2 proviruses encode viral proteins such as Env and Rec. RESULTS: We describe here that HML-2 Env gives rise to a 13 kDa signal peptide (SP) that harbors a different C-te...

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Detalles Bibliográficos
Autores principales: Ruggieri, Alessia, Maldener, Esther, Sauter, Marlies, Mueller-Lantzsch, Nikolaus, Meese, Eckart, Fackler, Oliver T, Mayer, Jens
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649029/
https://www.ncbi.nlm.nih.gov/pubmed/19220907
http://dx.doi.org/10.1186/1742-4690-6-17