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Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex
BACKGROUND: Adenomatous polyposis coli (Apc) is a large multifunctional protein known to be important for Wnt/β-catenin signalling, cytoskeletal dynamics, and cell polarity. In the developing cerebral cortex, Apc is expressed in proliferating cells and its expression increases as cells migrate to th...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649069/ https://www.ncbi.nlm.nih.gov/pubmed/19149881 http://dx.doi.org/10.1186/1749-8104-4-3 |