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Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex

BACKGROUND: Adenomatous polyposis coli (Apc) is a large multifunctional protein known to be important for Wnt/β-catenin signalling, cytoskeletal dynamics, and cell polarity. In the developing cerebral cortex, Apc is expressed in proliferating cells and its expression increases as cells migrate to th...

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Detalles Bibliográficos
Autores principales: Ivaniutsin, Uladzislau, Chen, Yijing, Mason, John O, Price, David J, Pratt, Thomas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649069/
https://www.ncbi.nlm.nih.gov/pubmed/19149881
http://dx.doi.org/10.1186/1749-8104-4-3