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Disease-associated pathophysiologic structures in pediatric rheumatic diseases show characteristics of scale-free networks seen in physiologic systems: implications for pathogenesis and treatment

BACKGROUND: While standard reductionist approaches have provided some insights into specific gene polymorphisms and molecular pathways involved in disease pathogenesis, our understanding of complex traits such as atherosclerosis or type 2 diabetes remains incomplete. Gene expression profiling provid...

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Detalles Bibliográficos
Autores principales: Frank, Mark Barton, Wang, Shirley, Aggarwal, Amita, Knowlton, Nicholas, Jiang, Kaiyu, Chen, Yanmin, McKee, Ryan, Chaser, Brad, McGhee, Timothy, Osban, Jeanette, Jarvis, James N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649160/
https://www.ncbi.nlm.nih.gov/pubmed/19236715
http://dx.doi.org/10.1186/1755-8794-2-9