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Disease-associated pathophysiologic structures in pediatric rheumatic diseases show characteristics of scale-free networks seen in physiologic systems: implications for pathogenesis and treatment
BACKGROUND: While standard reductionist approaches have provided some insights into specific gene polymorphisms and molecular pathways involved in disease pathogenesis, our understanding of complex traits such as atherosclerosis or type 2 diabetes remains incomplete. Gene expression profiling provid...
Autores principales: | Frank, Mark Barton, Wang, Shirley, Aggarwal, Amita, Knowlton, Nicholas, Jiang, Kaiyu, Chen, Yanmin, McKee, Ryan, Chaser, Brad, McGhee, Timothy, Osban, Jeanette, Jarvis, James N |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649160/ https://www.ncbi.nlm.nih.gov/pubmed/19236715 http://dx.doi.org/10.1186/1755-8794-2-9 |
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