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Efficacy of Simple Short-Term in Vitro Assays for Predicting the Potential of Metal Oxide Nanoparticles to Cause Pulmonary Inflammation

BACKGROUND: There has been concern regarding risks from inhalation exposure to nanoparticles (NPs). The large number of particles requiring testing means that alternative approaches to animal testing are needed. OBJECTIVES: We set out to determine whether short-term in vitro assays that assess intri...

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Detalles Bibliográficos
Autores principales: Lu, Senlin, Duffin, Rodger, Poland, Craig, Daly, Paul, Murphy, Fiona, Drost, Ellen, MacNee, William, Stone, Vicki, Donaldson, Ken
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649226/
https://www.ncbi.nlm.nih.gov/pubmed/19270794
http://dx.doi.org/10.1289/ehp.11811