Folate Deficiency, Hyperhomocysteinemia, Low Urinary Creatinine, and Hypomethylation of Leukocyte DNA Are Risk Factors for Arsenic-Induced Skin Lesions

BACKGROUND: Arsenic methylation relies on folate-dependent one-carbon metabolism and facilitates urinary As elimination. Clinical manifestations of As toxicity vary considerably among individuals and populations, and poor methylation capacity is thought to confer greater susceptibility. OBJECTIVE: A...

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Detalles Bibliográficos
Autores principales: Pilsner, J. Richard, Liu, Xinhua, Ahsan, Habibul, Ilievski, Vesna, Slavkovich, Vesna, Levy, Diane, Factor-Litvak, Pam, Graziano, Joseph H., Gamble, Mary V.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649228/
https://www.ncbi.nlm.nih.gov/pubmed/19270796
http://dx.doi.org/10.1289/ehp.11872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649228/
https://www.ncbi.nlm.nih.gov/pubmed/19270796
http://dx.doi.org/10.1289/ehp.11872

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