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Comparative Proteomic Phenotyping of Cell Lines and Primary Cells to Assess Preservation of Cell Type-specific Functions

Biological experiments are most often performed with immortalized cell lines because they are readily available and can be expanded without limitation. However, cell lines may differ from the in vivo situation in important aspects. Here we introduce a straightforward methodology to compare cell line...

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Detalles Bibliográficos
Autores principales: Pan, Cuiping, Kumar, Chanchal, Bohl, Sebastian, Klingmueller, Ursula, Mann, Matthias
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649808/
https://www.ncbi.nlm.nih.gov/pubmed/18952599
http://dx.doi.org/10.1074/mcp.M800258-MCP200