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Binding of long-chain α-neurotoxin would stabilize the resting state of nAChR: A comparative study with α-conotoxin

BACKGROUND: The details of interaction in a complex between potent antagonists such as long chain α-neurotoxins and α-conotoxins with nicotinic acetylcholine receptor (nAChR), and conformational changes induced by these antagonists, are not yet clear. MODELING: In order to uncover some of these crit...

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Detalles Bibliográficos
Autores principales: Nasiripourdori, Adak, Ranjbar, Bijan, Naderi-Manesh, Hossein
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649906/
https://www.ncbi.nlm.nih.gov/pubmed/19210780
http://dx.doi.org/10.1186/1742-4682-6-3