Bipotential mouse embryonic liver (BMEL) cells spontaneously express Pdx1 and Ngn3 but do not undergo further pancreatic differentiation upon Hes1 down-regulation

BACKGROUND: Liver-to-pancreas conversion offers new possibilities for β-cell engineering for type 1 diabetes therapy. Among conceivable sources of liver cells, we focused on BMEL cells. These untransformed mouse embryonic liver cells have been reproducibly isolated from different inbred mice strains...

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Detalles Bibliográficos
Autores principales: Delisle, Juliette Cuvelier, Martignat, Lionel, Bach, Jean-Marie, Bösch, Steffi, Louzier, Vanessa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649931/
https://www.ncbi.nlm.nih.gov/pubmed/19108739
http://dx.doi.org/10.1186/1756-0500-1-136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649931/
https://www.ncbi.nlm.nih.gov/pubmed/19108739
http://dx.doi.org/10.1186/1756-0500-1-136

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