High quality copy number and genotype data from FFPE samples using Molecular Inversion Probe (MIP) microarrays

BACKGROUND: A major challenge facing DNA copy number (CN) studies of tumors is that most banked samples with extensive clinical follow-up information are Formalin-Fixed Paraffin Embedded (FFPE). DNA from FFPE samples generally underperforms or suffers high failure rates compared to fresh frozen samp...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yuker, Carlton, Victoria EH, Karlin-Neumann, George, Sapolsky, Ronald, Zhang, Li, Moorhead, Martin, Wang, Zhigang C, Richardson, Andrea L, Warren, Robert, Walther, Axel, Bondy, Melissa, Sahin, Aysegul, Krahe, Ralf, Tuna, Musaffe, Thompson, Patricia A, Spellman, Paul T, Gray, Joe W, Mills, Gordon B, Faham, Malek
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649948/
https://www.ncbi.nlm.nih.gov/pubmed/19228381
http://dx.doi.org/10.1186/1755-8794-2-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649948/
https://www.ncbi.nlm.nih.gov/pubmed/19228381
http://dx.doi.org/10.1186/1755-8794-2-8

Ejemplares similares