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Transcript-Specific Expression Profiles Derived from Sequence-Based Analysis of Standard Microarrays

BACKGROUND: Alternative mRNA processing mechanisms lead to multiple transcripts (i.e. splice isoforms) of a given gene which may have distinct biological functions. Microarrays like Affymetrix GeneChips measure mRNA expression of genes using sets of nucleotide probes. Until recently probe sets were...

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Detalles Bibliográficos
Autores principales: Moll, Anton G., Lindenmeyer, Maja T., Kretzler, Matthias, Nelson, Peter J., Zimmer, Ralf, Cohen, Clemens D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650090/
https://www.ncbi.nlm.nih.gov/pubmed/19277110
http://dx.doi.org/10.1371/journal.pone.0004702