Identification of stable S-adenosylmethionine (SAM) analogues derivatised with bioorthogonal tags: effect of ligands on the affinity of the E. coli methionine repressor, MetJ, for its operator DNA

The efficient synthesis of a range of stable SAM mimetics, and their ability to promote the binding of the E. coli methionine repressor (MetJ) to its operator DNA, is described.

Detalles Bibliográficos
Autores principales: Joce, Catherine, Caryl, Jamie, Stockley, Peter G., Warriner, Stuart, Nelson, Adam
Formato: Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2009
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650099/
https://www.ncbi.nlm.nih.gov/pubmed/19194573
http://dx.doi.org/10.1039/b816495a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650099/
https://www.ncbi.nlm.nih.gov/pubmed/19194573
http://dx.doi.org/10.1039/b816495a

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