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RNA Modulators of Complex Phenotypes in Mammalian Cells

RNA-mediated gene silencing, in the form of RNA interference (RNAi) or microRNAs (miRNAs) has provided novel tools for gene discovery and validation in mammalian cells. Here, we report on the construction and application of a random small RNA expression library for use in identifying small interferi...

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Detalles Bibliográficos
Autores principales: Lai, Angela, Cairns, Murray J., Tran, Nham, Zhang, Hong-Ping, Cullen, Lara, Arndt, Greg M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650256/
https://www.ncbi.nlm.nih.gov/pubmed/19270743
http://dx.doi.org/10.1371/journal.pone.0004758