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Ciliary Beating Recovery in Deficient Human Airway Epithelial Cells after Lentivirus Ex Vivo Gene Therapy

Primary Ciliary Dyskinesia is a heterogeneous genetic disease that is characterized by cilia dysfunction of the epithelial cells lining the respiratory tracts, resulting in recurrent respiratory tract infections. Despite lifelong physiological therapy and antibiotics, the lungs of affected patients...

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Detalles Bibliográficos
Autores principales: Chhin, Brigitte, Negre, Didier, Merrot, Olivier, Pham, Jacqueline, Tourneur, Yves, Ressnikoff, Denis, Jaspers, Martine, Jorissen, Mark, Cosset, François-Loïc, Bouvagnet, Patrice
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650261/
https://www.ncbi.nlm.nih.gov/pubmed/19300481
http://dx.doi.org/10.1371/journal.pgen.1000422