A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci

There is considerable variability in the susceptibility of smokers to develop chronic obstructive pulmonary disease (COPD). The only known genetic risk factor is severe deficiency of α(1)-antitrypsin, which is present in 1–2% of individuals with COPD. We conducted a genome-wide association study (GW...

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Detalles Bibliográficos
Autores principales: Pillai, Sreekumar G., Ge, Dongliang, Zhu, Guohua, Kong, Xiangyang, Shianna, Kevin V., Need, Anna C., Feng, Sheng, Hersh, Craig P., Bakke, Per, Gulsvik, Amund, Ruppert, Andreas, Lødrup Carlsen, Karin C., Roses, Allen, Anderson, Wayne, Rennard, Stephen I., Lomas, David A., Silverman, Edwin K., Goldstein, David B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650282/
https://www.ncbi.nlm.nih.gov/pubmed/19300482
http://dx.doi.org/10.1371/journal.pgen.1000421

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