A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci

There is considerable variability in the susceptibility of smokers to develop chronic obstructive pulmonary disease (COPD). The only known genetic risk factor is severe deficiency of α(1)-antitrypsin, which is present in 1–2% of individuals with COPD. We conducted a genome-wide association study (GW...

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Détails bibliographiques
Auteurs principaux: Pillai, Sreekumar G., Ge, Dongliang, Zhu, Guohua, Kong, Xiangyang, Shianna, Kevin V., Need, Anna C., Feng, Sheng, Hersh, Craig P., Bakke, Per, Gulsvik, Amund, Ruppert, Andreas, Lødrup Carlsen, Karin C., Roses, Allen, Anderson, Wayne, Rennard, Stephen I., Lomas, David A., Silverman, Edwin K., Goldstein, David B.
Format: Texte
Langue:English
Publié: Public Library of Science 2009
Sujets:
Research Article
Accès en ligne:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650282/
https://www.ncbi.nlm.nih.gov/pubmed/19300482
http://dx.doi.org/10.1371/journal.pgen.1000421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650282/
https://www.ncbi.nlm.nih.gov/pubmed/19300482
http://dx.doi.org/10.1371/journal.pgen.1000421

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