A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci

There is considerable variability in the susceptibility of smokers to develop chronic obstructive pulmonary disease (COPD). The only known genetic risk factor is severe deficiency of α(1)-antitrypsin, which is present in 1–2% of individuals with COPD. We conducted a genome-wide association study (GW...

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Detalhes bibliográficos
Autores principales: Pillai, Sreekumar G., Ge, Dongliang, Zhu, Guohua, Kong, Xiangyang, Shianna, Kevin V., Need, Anna C., Feng, Sheng, Hersh, Craig P., Bakke, Per, Gulsvik, Amund, Ruppert, Andreas, Lødrup Carlsen, Karin C., Roses, Allen, Anderson, Wayne, Rennard, Stephen I., Lomas, David A., Silverman, Edwin K., Goldstein, David B.
Formato: Texto
Idioma:English
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650282/
https://www.ncbi.nlm.nih.gov/pubmed/19300482
http://dx.doi.org/10.1371/journal.pgen.1000421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650282/
https://www.ncbi.nlm.nih.gov/pubmed/19300482
http://dx.doi.org/10.1371/journal.pgen.1000421

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