New Symmetrically Esterified m-Bromobenzyl Non-Aminobisphosphonates Inhibited Breast Cancer Growth and Metastases

BACKGROUND: Although there was growing evidence in the potential use of Bisphosphonates (BPs) in cancer therapy, their strong osseous affinities that contrast their poor soft tissue uptake limited their use. Here, we developed a new strategy to overcome BPs hydrophilicity by masking the phosphonic a...

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Detalles Bibliográficos
Autores principales: Abdelkarim, Mohamed, Guenin, Erwann, Sainte-Catherine, Odile, Vintonenko, Nadejda, Peyri, Nicole, Perret, Gerard Yves, Crepin, Michel, Khatib, Abdel-Majid, Lecouvey, Marc, Di Benedetto, Mélanie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650402/
https://www.ncbi.nlm.nih.gov/pubmed/19262688
http://dx.doi.org/10.1371/journal.pone.0004685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650402/
https://www.ncbi.nlm.nih.gov/pubmed/19262688
http://dx.doi.org/10.1371/journal.pone.0004685

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