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T-Cell Epitope Prediction: Rescaling Can Mask Biological Variation between MHC Molecules

Theoretical methods for predicting CD8+ T-cell epitopes are an important tool in vaccine design and for enhancing our understanding of the cellular immune system. The most popular methods currently available produce binding affinity predictions across a range of MHC molecules. In comparing results b...

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Detalles Bibliográficos
Autores principales: MacNamara, Aidan, Kadolsky, Ulrich, Bangham, Charles R. M., Asquith, Becca
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650421/
https://www.ncbi.nlm.nih.gov/pubmed/19300484
http://dx.doi.org/10.1371/journal.pcbi.1000327