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ABCD of the phosphodiesterase family: interaction and differential activity in COPD
Phosphodiesterases (PDEs) are important enzymes that hydrolyze the cyclic nucleotides adenosine 3′5′-cyclic monophosphate (cAMP) and guanosine 3′5′-cyclic mono-phosphate (cGMP) to their inactive 5′ monophosphates. They are highly conserved across species and as well as their role in signal terminati...
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| Formato: | Texto |
| Lenguaje: | English |
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Dove Medical Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650605/ https://www.ncbi.nlm.nih.gov/pubmed/19281073 |