Fludarabine Modulates Immune Response and Extends In Vivo Survival of Adoptively Transferred CD8 T Cells in Patients with Metastatic Melanoma

BACKGROUND: Adoptive T cell therapy involving the use of ex vivo generated antigen-specific cytotoxic T lymphocytes provides a promising approach to immunotherapy. It has become increasingly apparent that anti-tumor efficacy using adoptively transferred T cells is linked to their duration of in vivo...

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Detalles Bibliográficos
Autores principales: Wallen, Herschel, Thompson, John A., Reilly, J. Zachary, Rodmyre, Rebecca M., Cao, Jianhong, Yee, Cassian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650617/
https://www.ncbi.nlm.nih.gov/pubmed/19270751
http://dx.doi.org/10.1371/journal.pone.0004749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650617/
https://www.ncbi.nlm.nih.gov/pubmed/19270751
http://dx.doi.org/10.1371/journal.pone.0004749

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