The centrosome protein NEDD1 as a potential pharmacological target to induce cell cycle arrest

BACKGROUND: NEDD1 is a protein that binds to the gamma-tubulin ring complex, a multiprotein complex at the centrosome and at the mitotic spindle that mediates the nucleation of microtubules. RESULTS: We show that NEDD1 is expressed at comparable levels in a variety of tumor-derived cell lines and un...

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Detalles Bibliográficos
Autores principales: Tillement, Vanessa, Haren, Laurence, Roullet, Nicolas, Etievant, Chantal, Merdes, Andreas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650675/
https://www.ncbi.nlm.nih.gov/pubmed/19243593
http://dx.doi.org/10.1186/1476-4598-8-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650675/
https://www.ncbi.nlm.nih.gov/pubmed/19243593
http://dx.doi.org/10.1186/1476-4598-8-10

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