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Expression of verotoxin-1 receptor Gb3 in breast cancer tissue and verotoxin-1 signal transduction to apoptosis

BACKGROUND: The prerequisite for the potential use of the bacterial toxin verotoxin-1 in the treatment of breast cancer was investigated by first determining the expression of its receptor Gb3 (CD77) in clinical breast cancer tissue specimens. We then examined the cytotoxicity and mechanism of apopt...

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Detalles Bibliográficos
Autores principales: Johansson, David, Kosovac, Eldina, Moharer, Jasmin, Ljuslinder, Ingrid, Brännström, Thomas, Johansson, Anders, Behnam-Motlagh, Parviz
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650710/
https://www.ncbi.nlm.nih.gov/pubmed/19245689
http://dx.doi.org/10.1186/1471-2407-9-67