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DNA Methylation of the ABO Promoter Underlies Loss of ABO Allelic Expression in a Significant Proportion of Leukemic Patients

BACKGROUND: Loss of A, B and H antigens from the red blood cells of patients with myeloid malignancies is a frequent occurrence. Previously, we have reported alterations in ABH antigens on the red blood cells of 55% of patients with myeloid malignancies. METHODOLOGY/PRINCIPAL FINDINGS: To determine...

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Detalles Bibliográficos
Autores principales: Bianco-Miotto, Tina, Hussey, Damian J., Day, Tanya K., O'Keefe, Denise S., Dobrovic, Alexander
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650780/
https://www.ncbi.nlm.nih.gov/pubmed/19274076
http://dx.doi.org/10.1371/journal.pone.0004788