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Computing Highly Correlated Positions Using Mutual Information and Graph Theory for G Protein-Coupled Receptors
G protein-coupled receptors (GPCRs) are a superfamily of seven transmembrane-spanning proteins involved in a wide array of physiological functions and are the most common targets of pharmaceuticals. This study aims to identify a cohort or clique of positions that share high mutual information. Using...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650788/ https://www.ncbi.nlm.nih.gov/pubmed/19262747 http://dx.doi.org/10.1371/journal.pone.0004681 |