Active site substitutions delineate distinct classes of eubacterial flap endonuclease

FENs (flap endonucleases) play essential roles in DNA replication, pivotally in the resolution of Okazaki fragments. In eubacteria, DNA PolI (polymerase I) contains a flap processing domain, the N-terminal 5′→3′ exonuclease. We present evidence of paralogous FEN-encoding genes present in many eubact...

Descripción completa

Detalles Bibliográficos
Autores principales: Allen, Lee M., Hodskinson, Michael R. G., Sayers, Jon R.
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650880/
https://www.ncbi.nlm.nih.gov/pubmed/19000038
http://dx.doi.org/10.1042/BJ20081637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650880/
https://www.ncbi.nlm.nih.gov/pubmed/19000038
http://dx.doi.org/10.1042/BJ20081637

Ejemplares similares