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Simulation of the AUC Changes after Generic Substitution in Patients
To address the debate on the safety of generic substitution quantitatively, the author compared the change in AUC in virtual patients who were simulated for several different scenarios of generic substitution. In four scenarios of original (branded) to generic and generic to generic substitution, 5,...
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Korean Academy of Medical Sciences
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650971/ https://www.ncbi.nlm.nih.gov/pubmed/19270806 http://dx.doi.org/10.3346/jkms.2009.24.1.7 |