Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1

Type 5 adenovirus (Ad5) is a human pathogen that has been widely developed for therapeutic uses, with only limited success to date. We report here the novel finding that human erythrocytes present Coxsackie virus-adenovirus receptor (CAR) providing an Ad5 sequestration mechanism that protects agains...

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Detalles Bibliográficos
Autores principales: Carlisle, Robert C., Di, Ying, Cerny, Anna M., Sonnen, Andreas F.-P., Sim, Robert B., Green, Nicola K., Subr, Vladimir, Ulbrich, Karel, Gilbert, Robert J. C., Fisher, Kerry D., Finberg, Robert W., Seymour, Leonard W.
Formato: Texto
Lenguaje:English
Publicado: American Society of Hematology 2009
Materias:
Gene Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651010/
https://www.ncbi.nlm.nih.gov/pubmed/19131551
http://dx.doi.org/10.1182/blood-2008-09-178459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651010/
https://www.ncbi.nlm.nih.gov/pubmed/19131551
http://dx.doi.org/10.1182/blood-2008-09-178459

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