Cargando…

Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1

Type 5 adenovirus (Ad5) is a human pathogen that has been widely developed for therapeutic uses, with only limited success to date. We report here the novel finding that human erythrocytes present Coxsackie virus-adenovirus receptor (CAR) providing an Ad5 sequestration mechanism that protects agains...

Descripción completa

Detalles Bibliográficos
Autores principales:	Carlisle, Robert C., Di, Ying, Cerny, Anna M., Sonnen, Andreas F.-P., Sim, Robert B., Green, Nicola K., Subr, Vladimir, Ulbrich, Karel, Gilbert, Robert J. C., Fisher, Kerry D., Finberg, Robert W., Seymour, Leonard W.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society of Hematology 2009
Materias:	Gene Therapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651010/ https://www.ncbi.nlm.nih.gov/pubmed/19131551 http://dx.doi.org/10.1182/blood-2008-09-178459

Ejemplares similares

Loss of the coxsackie and adenovirus receptor contributes to gastric cancer progression
por: Anders, M, et al.
Publicado: (2009)

Targeting adenovirus gene delivery to activated tumour-associated vasculature via endothelial selectins
por: Bachtarzi, Houria, et al.
Publicado: (2011)

Loss of Coxsackie and adenovirus receptor downregulates α-catenin expression
por: Stecker, K, et al.
Publicado: (2009)

Protective Role of Coxsackie-Adenovirus Receptor in the Pathogenesis of Inflammatory Bowel Diseases
por: Chen, Xiong, et al.
Publicado: (2018)

Human Adenovirus 52 Uses Sialic Acid-containing Glycoproteins and the Coxsackie and Adenovirus Receptor for Binding to Target Cells
por: Lenman, Annasara, et al.
Publicado: (2015)

ZEB1 limits adenoviral infectability by transcriptionally repressing the Coxsackie virus and Adenovirus Receptor
por: Lacher, Markus D, et al.
Publicado: (2011)

Essential Role of the Coxsackie - and Adenovirus Receptor (CAR) in Development of the Lymphatic System in Mice
por: Mirza, Momina, et al.
Publicado: (2012)

Isoform-Specific Regulation and Localization of the Coxsackie and Adenovirus Receptor in Human Airway Epithelia
por: Excoffon, Katherine J. D. A., et al.
Publicado: (2010)

Efficient adenovirus-mediated gene transfer into primary T cells and thymocytes in a new coxsackie/adenovirus receptor transgenic model
por: Hurez, Vincent, et al.
Publicado: (2002)

Coxsackie–adenovirus receptor expression is enhanced in pancreas from patients with type 1 diabetes
por: Hodik, M, et al.
Publicado: (2016)

Human Coxsackie- and adenovirus receptor is a putative target of neutrophil elastase-mediated shedding
por: Herrmann, Leonie, et al.
Publicado: (2022)

Isoform-specific expression of the Coxsackie and adenovirus receptor (CAR) in neuromuscular junction and cardiac intercalated discs
por: Shaw, Christian A, et al.
Publicado: (2004)

Expression of coxsackie and adenovirus receptor distinguishes transitional cancer states in therapy-induced cellular senescence
por: Wu, P C, et al.
Publicado: (2010)

Transcription Factor Sp1 Is Involved in Expressional Regulation of Coxsackie and Adenovirus Receptor in Cancer Cells
por: Chung, Sun-Ku, et al.
Publicado: (2011)

Study of Coxsackie B viruses interactions with Coxsackie Adenovirus receptor and Decay-Accelerating Factor using Human CaCo-2 cell line
por: Riabi, Samira, et al.
Publicado: (2014)

FURTHER CHARACTERIZATION OF THE ADENOVIRUS ERYTHROCYTE RECEPTOR-MODIFYING FACTOR
por: Kasel, Julius A., et al.
Publicado: (1961)

A novel monoclonal antibody targeting coxsackie virus and adenovirus receptor inhibits tumor growth in vivo
por: Kawada, Manabu, et al.
Publicado: (2017)

Upregulation of Coxsackie Adenovirus Receptor Sensitizes Cisplatin-Resistant Lung Cancer Cells to CRAd-Induced Inhibition
por: Sakhawat, Ali, et al.
Publicado: (2017)

ERK1/2 pathway regulates coxsackie and adenovirus receptor expression in mouse cardiac stem cells
por: Liu, Jingjin, et al.
Publicado: (2017)

Extracellular Vesicles-Mimetic Encapsulation Improves Oncolytic Viro-Immunotherapy in Tumors With Low Coxsackie and Adenovirus Receptor
por: Zhang, Yonghui, et al.
Publicado: (2020)

Loss of coxsackie and adenovirus receptor expression in human colorectal cancer: A potential impact on the efficacy of adenovirus-mediated gene therapy in Chinese Han population
por: Ma, Ying-Yu, et al.
Publicado: (2016)

Complement Receptor 1 Is a Sialic Acid-Independent Erythrocyte Receptor of Plasmodium falciparum
por: Spadafora, Carmenza, et al.
Publicado: (2010)

Marine Lectins DlFBL and HddSBL Fused with Soluble Coxsackie-Adenovirus Receptor Facilitate Adenovirus Infection in Cancer Cells BUT Have Different Effects on Cell Survival
por: Wu, Bingbing, et al.
Publicado: (2017)

THER-09. ONCOLYTIC ADENOVIRUS, DNX-2401, FOR NAIVE DIFFUSE INTRINSIC PONTINE GLIOMAS: A PHASE I CLINICAL TRIAL
por: Iñigo-Marco, Ignacio, et al.
Publicado: (2020)

Traceless Bioresponsive Shielding of Adenovirus Hexon with HPMA Copolymers Maintains Transduction Capacity In Vitro and In Vivo
por: Prill, Jan-Michael, et al.
Publicado: (2014)

Unexpected subcellular distribution of a specific isoform of the Coxsackie and adenovirus receptor, CAR-SIV, in human pancreatic beta cells
por: Ifie, Eseoghene, et al.
Publicado: (2018)

The Cell Adhesion Molecule “CAR” and Sialic Acid on Human Erythrocytes Influence Adenovirus In Vivo Biodistribution
por: Seiradake, Elena, et al.
Publicado: (2009)

Prognostic impact of corticosteroids on efficacy of chimeric antigen receptor T-cell therapy in large B-cell lymphoma
por: Strati, Paolo, et al.
Publicado: (2021)

Stable and durable factor IX levels in patients with hemophilia B over 3 years after etranacogene dezaparvovec gene therapy
por: von Drygalski, Annette, et al.
Publicado: (2022)

Complement activation by recombinant adenoviruses
por: Cichon, G, et al.
Publicado: (2002)

Expression of human CD46 and trans-complementation by murine adenovirus 1 fails to allow productive infection by a group B oncolytic adenovirus in murine cancer cells
por: Lei, Janet, et al.
Publicado: (2018)

Histone Deacetylase Inhibitors Restore Cell Surface Expression of the Coxsackie Adenovirus Receptor and Enhance CMV Promoter Activity in Castration-Resistant Prostate Cancer Cells
por: Kasman, Laura, et al.
Publicado: (2012)

Enhanced Tumor Uptake and Penetration of Virotherapy Using Polymer Stealthing and Focused Ultrasound
por: Carlisle, Robert, et al.
Publicado: (2013)

Adenovirus Receptor Expression in Cancer and Its Multifaceted Role in Oncolytic Adenovirus Therapy
por: Hensen, Lobke C.M., et al.
Publicado: (2020)

Adenovirus receptors and their implications in gene delivery
por: Sharma, Anurag, et al.
Publicado: (2009)

Contributions of coxsackievirus adenovirus receptor to tumorigenesis
por: Owczarek, Claudia, et al.
Publicado: (2023)

Identification of novel human adenovirus candidates using the coxsackievirus and adenovirus receptor for cell entry
por: Mese, Kemal, et al.
Publicado: (2020)

AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage
por: Binny, Christopher, et al.
Publicado: (2012)

Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells
por: Zhang, Fang, et al.
Publicado: (2007)

CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells
por: Flynn, Rowan, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ispqg3r32dienc6jo2j2v6prgu