Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus

BACKGROUND: Hepatitis C virus (HCV) infection is a global health problem. A number of studies have implicated a direct role of cellular lipid metabolism in the HCV life cycle and inhibitors of the mevalonate pathway have been demonstrated to result in an antiviral state within the host cell. Transcr...

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Detalles Bibliográficos
Autores principales: Pezacki, John Paul, Sagan, Selena M, Tonary, Angela M, Rouleau, Yanouchka, Bélanger, Sylvie, Supekova, Lubica, Su, Andrew I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651120/
https://www.ncbi.nlm.nih.gov/pubmed/19149867
http://dx.doi.org/10.1186/1472-6769-9-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651120/
https://www.ncbi.nlm.nih.gov/pubmed/19149867
http://dx.doi.org/10.1186/1472-6769-9-2

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