Cargando…

Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus

BACKGROUND: Hepatitis C virus (HCV) infection is a global health problem. A number of studies have implicated a direct role of cellular lipid metabolism in the HCV life cycle and inhibitors of the mevalonate pathway have been demonstrated to result in an antiviral state within the host cell. Transcr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pezacki, John Paul, Sagan, Selena M, Tonary, Angela M, Rouleau, Yanouchka, Bélanger, Sylvie, Supekova, Lubica, Su, Andrew I
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651120/ https://www.ncbi.nlm.nih.gov/pubmed/19149867 http://dx.doi.org/10.1186/1472-6769-9-2

Ejemplares similares

25-hydroxycholesterol: an integrator of antiviral ability and signaling
por: Zhang, Jialu, et al.
Publicado: (2023)

25-Hydroxycholesterol 3-sulfate is an endogenous ligand of DNA methyltransferases in hepatocytes
por: Wang, Yaping, et al.
Publicado: (2021)

The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response
por: Blanc, Mathieu, et al.
Publicado: (2013)

Antiviral Actions of 25-Hydroxycholesterol in Fish Vary With the Virus-Host Combination
por: Adamek, Mikolaj, et al.
Publicado: (2021)

Modulation of cell proteome by 25-hydroxycholesterol and 27-hydroxycholesterol: A link between cholesterol metabolism and antiviral defense
por: Civra, Andrea, et al.
Publicado: (2020)

Inhibition of pathogenic non-enveloped viruses by 25-hydroxycholesterol and 27-hydroxycholesterol
por: Civra, Andrea, et al.
Publicado: (2014)

Inhibition of herpes simplex-1 virus replication by 25-hydroxycholesterol and 27-hydroxycholesterol
por: Cagno, Valeria, et al.
Publicado: (2017)

Inhibition of Marek’s Disease Virus Replication and Spread by 25-hydroxycholesterol and 27-hydroxycholesterol In Vitro
por: Kamble, Nitin, et al.
Publicado: (2023)

Biophysical Properties and Antiviral Activities of Measles Fusion Protein Derived Peptide Conjugated with 25-Hydroxycholesterol
por: Gomes, Bárbara, et al.
Publicado: (2017)

Cholesterol Metabolites 25-Hydroxycholesterol and 25-Hydroxycholesterol 3-Sulfate Are Potent Paired Regulators: From Discovery to Clinical Usage
por: Wang, Yaping, et al.
Publicado: (2020)

Studies in the antiviral molecular mechanisms of 25-hydroxycholesterol: Disturbing cholesterol homeostasis and post-translational modification of proteins
por: Mao, Shijie, et al.
Publicado: (2022)

25-Hydroxycholesterol as a Signaling Molecule of the Nervous System
por: Odnoshivkina, Ulia G., et al.
Publicado: (2022)

25-Hydroxycholesterol Effect on Membrane Structure and Mechanical Properties
por: Domingues, Marco M., et al.
Publicado: (2021)

25-Hydroxycholesterol and 27-hydroxycholesterol inhibit human rotavirus infection by sequestering viral particles into late endosomes
por: Civra, Andrea, et al.
Publicado: (2018)

24S-hydroxycholesterol and 25-hydroxycholesterol differentially impact hippocampal neuronal survival following oxygen-glucose deprivation
por: Sun, Min-Yu, et al.
Publicado: (2017)

Modulation of Antiviral Immunity and Therapeutic Efficacy by 25-Hydroxycholesterol in Chronically SIV-Infected, ART-Treated Rhesus Macaques
por: Wu, Chunxiu, et al.
Publicado: (2021)

The Oxysterol 25-Hydroxycholesterol Inhibits Replication of Murine Norovirus
por: Shawli, Ghada T., et al.
Publicado: (2019)

25-Hydroxycholesterol is involved in the pathogenesis of amyotrophic lateral sclerosis
por: Kim, Sung-Min, et al.
Publicado: (2017)

Oncogenic roles of the cholesterol metabolite 25-hydroxycholesterol in bladder cancer
por: Wang, Chen, et al.
Publicado: (2020)

25-Hydroxycholesterol exacerbates vascular leak during acute lung injury
por: Madenspacher, Jennifer H., et al.
Publicado: (2023)

Viral MicroRNAs Repress the Cholesterol Pathway, and 25-Hydroxycholesterol Inhibits Infection
por: Serquiña, Anna K. P., et al.
Publicado: (2017)

Regulating Innate and Adaptive Immunity for Controlling SIV Infection by 25-Hydroxycholesterol
por: Wu, Tongjin, et al.
Publicado: (2018)

25-Hydroxycholesterol is a potent SARS-CoV-2 inhibitor
por: Zu, Shulong, et al.
Publicado: (2020)

Senolysis induced by 25-hydroxycholesterol targets CRYAB in multiple cell types
por: Limbad, Chandani, et al.
Publicado: (2022)

Serum 25-hydroxycholesterol levels are increased in patients with coronavirus disease 2019()
por: Asano, Takumi, et al.
Publicado: (2023)

Cholesterol 25-hydroxylase negatively regulates porcine intestinal coronavirus replication by the production of 25-hydroxycholesterol
por: Zhang, Yunhang, et al.
Publicado: (2019)

Cholesterol 25-hydroxylase suppresses avian reovirus replication by its enzymatic product 25-hydroxycholesterol
por: Wang, Yuyang, et al.
Publicado: (2023)

RORα and 25-Hydroxycholesterol Crosstalk Regulates Lipid Droplet Homeostasis in Macrophages
por: Tuong, Zewen Kelvin, et al.
Publicado: (2016)

Integrin activation by the lipid molecule 25-hydroxycholesterol induces a proinflammatory response
por: Pokharel, Swechha M., et al.
Publicado: (2019)

Oxysterol binding protein-related protein 8 mediates the cytotoxicity of 25-hydroxycholesterol
por: Li, Jiwei, et al.
Publicado: (2016)

25-Hydroxycholesterol-Induced Oxiapoptophagy in L929 Mouse Fibroblast Cell Line
por: You, Jae-Seek, et al.
Publicado: (2021)

SGLT2 Inhibitors May Restore Endothelial Barrier Interrupted by 25-Hydroxycholesterol
por: Pawlos, Agnieszka, et al.
Publicado: (2023)

Cholesterol-25-hydroxylase Is a Chicken ISG That Restricts ALV-J Infection by Producing 25-hydroxycholesterol
por: Xie, Tingting, et al.
Publicado: (2019)

Quantitative detection of free 24S-hydroxycholesterol, and 27-hydroxycholesterol from human serum
por: Bandaru, Veera Venkata Ratnam, et al.
Publicado: (2014)

High Glucose Induces Lipid Accumulation via 25-Hydroxycholesterol DNA-CpG Methylation
por: Wang, Yaping, et al.
Publicado: (2020)

25-Hydroxycholesterol regulates cholesterol homeostasis in the murine CATH.a neuronal cell line
por: Waltl, Sabine, et al.
Publicado: (2013)

25-Hydroxycholesterol Inhibition of Lassa Virus Infection through Aberrant GP1 Glycosylation
por: Shrivastava-Ranjan, Punya, et al.
Publicado: (2016)

25‐Hydroxycholesterol protects against acute lung injury via targeting MD‐2
por: Ouyang, Wei, et al.
Publicado: (2018)

25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner
por: Wong, Man Ying, et al.
Publicado: (2020)

ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol–induced lipid body formation
por: Gold, Elizabeth S., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_59ls3e5elub8evep19oav29r9d