Cargando…
Structure of the Nucleotide Radical Formed during Reaction of CDP/TTP with the E441Q-α2β2 of E. coli Ribonucleotide Reductase
[Image: see text] The Escherichia coli ribonucleotide reductase (RNR) catalyzes the conversion of nucleoside diphosphates to deoxynucleotides and requires a diferric-tyrosyl radical cofactor for catalysis. RNR is composed of a 1:1 complex of two homodimeric subunits: α and β. Incubation of the E441Q...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2008
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651750/ https://www.ncbi.nlm.nih.gov/pubmed/19128178 http://dx.doi.org/10.1021/ja806693s |