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A genetic screen for components of the mammalian RNA interference pathway in Bloom-deficient mouse embryonic stem cells

Genetic screens performed in model organisms have helped identify key components of the RNA interference (RNAi) pathway. Recessive genetic screens have recently become feasible through the use of mouse embryonic stem (ES) cells that are Bloom's syndrome protein (Blm) deficient. Here, we develop...

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Detalles Bibliográficos
Autores principales: Trombly, Melanie I., Su, Hong, Wang, Xiaozhong
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651804/
https://www.ncbi.nlm.nih.gov/pubmed/19223321
http://dx.doi.org/10.1093/nar/gkp019