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A genetic screen for components of the mammalian RNA interference pathway in Bloom-deficient mouse embryonic stem cells
Genetic screens performed in model organisms have helped identify key components of the RNA interference (RNAi) pathway. Recessive genetic screens have recently become feasible through the use of mouse embryonic stem (ES) cells that are Bloom's syndrome protein (Blm) deficient. Here, we develop...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651804/ https://www.ncbi.nlm.nih.gov/pubmed/19223321 http://dx.doi.org/10.1093/nar/gkp019 |