Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes

Chromatin immunoprecipitation (ChIP) studies were conducted in human hepatocytes treated with rifampicin in order to identify new pregnane-X receptor (PXR) target genes. Genes, both previously known to be involved and not known to be involved in drug disposition, with PXR response elements (PXREs) l...

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Detalles Bibliográficos
Autores principales: Hariparsad, Niresh, Chu, Xiaoyan, Yabut, Jocelyn, Labhart, Paul, Hartley, Dylan P., Dai, Xudong, Evers, Raymond
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651806/
https://www.ncbi.nlm.nih.gov/pubmed/19129222
http://dx.doi.org/10.1093/nar/gkn1047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651806/
https://www.ncbi.nlm.nih.gov/pubmed/19129222
http://dx.doi.org/10.1093/nar/gkn1047

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