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Identification of pregnane-X receptor target genes and coactivator and corepressor binding to promoter elements in human hepatocytes
Chromatin immunoprecipitation (ChIP) studies were conducted in human hepatocytes treated with rifampicin in order to identify new pregnane-X receptor (PXR) target genes. Genes, both previously known to be involved and not known to be involved in drug disposition, with PXR response elements (PXREs) l...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651806/ https://www.ncbi.nlm.nih.gov/pubmed/19129222 http://dx.doi.org/10.1093/nar/gkn1047 |