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Identification of genes differentially expressed as result of adenovirus type 5- and adenovirus type 12-transformation

BACKGROUND: Cells transformed by human adenoviruses (Ad) exhibit differential capacities to induce tumours in immunocompetent rodents; for example, Ad12-transformed rodent cells are oncogenic whereas Ad5-transformed cells are not. The E1A gene determines oncogenic phenotype, is a transcriptional reg...

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Detalles Bibliográficos
Autores principales: Strath, Janet, Georgopoulos, Lindsay J, Kellam, Paul, Blair, G Eric
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651901/
https://www.ncbi.nlm.nih.gov/pubmed/19200380
http://dx.doi.org/10.1186/1471-2164-10-67