Homogeneous MGMT Immunoreactivity Correlates with an Unmethylated MGMT Promoter Status in Brain Metastases of Various Solid Tumors

The O(6)-methylguanine-methyltransferase (MGMT) promoter methylation status is a predictive parameter for the response of malignant gliomas to alkylating agents such as temozolomide. First clinical reports on treating brain metastases with temozolomide describe varying effects. This may be due to th...

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Detalles Bibliográficos
Autores principales: Ingold, Barbara, Schraml, Peter, Heppner, Frank L., Moch, Holger
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652028/
https://www.ncbi.nlm.nih.gov/pubmed/19274096
http://dx.doi.org/10.1371/journal.pone.0004775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652028/
https://www.ncbi.nlm.nih.gov/pubmed/19274096
http://dx.doi.org/10.1371/journal.pone.0004775

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