A Plant-Derived Recombinant Human Glucocerebrosidase Enzyme—A Preclinical and Phase I Investigation

Gaucher disease is a progressive lysosomal storage disorder caused by the deficiency of glucocerebrosidase leading to the dysfunction in multiple organ systems. Intravenous enzyme replacement is the accepted standard of treatment. In the current report, we evaluate the safety and pharmacokinetics of...

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Detalles Bibliográficos
Autores principales: Aviezer, David, Brill-Almon, Einat, Shaaltiel, Yoseph, Hashmueli, Sharon, Bartfeld, Daniel, Mizrachi, Sarah, Liberman, Yael, Freeman, Arnold, Zimran, Ari, Galun, Eithan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652073/
https://www.ncbi.nlm.nih.gov/pubmed/19277123
http://dx.doi.org/10.1371/journal.pone.0004792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652073/
https://www.ncbi.nlm.nih.gov/pubmed/19277123
http://dx.doi.org/10.1371/journal.pone.0004792

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