Measures of Autozygosity in Decline: Globalization, Urbanization, and Its Implications for Medical Genetics

This research investigates the influence of demographic factors on human genetic sub-structure. In our discovery cohort, we show significant demographic trends for decreasing autozygosity associated with population variation in chronological age. Autozygosity, the genomic signature of consanguinity,...

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Bibliografiske detaljer
Autores principales: Nalls, Michael A., Simon-Sanchez, Javier, Gibbs, J. Raphael, Paisan-Ruiz, Coro, Bras, Jose Tomas, Tanaka, Toshiko, Matarin, Mar, Scholz, Sonja, Weitz, Charles, Harris, Tamara B., Ferrucci, Luigi, Hardy, John, Singleton, Andrew B.
Format: Texto
Sprog:English
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652078/
https://www.ncbi.nlm.nih.gov/pubmed/19282984
http://dx.doi.org/10.1371/journal.pgen.1000415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652078/
https://www.ncbi.nlm.nih.gov/pubmed/19282984
http://dx.doi.org/10.1371/journal.pgen.1000415

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