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Reassessing the Role of APOBEC3G in Human Immunodeficiency Virus Type 1 Infection of Quiescent CD4+ T-Cells

HIV-1 is restricted for infection of primary quiescent T-cells. After viral entry, reverse transcription is initiated but is not completed. Various hypotheses have been proposed for this cellular restriction including insufficient nucleotide pools and cellular factors, but none have been confirmed a...

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Detalles Bibliográficos
Autores principales: Kamata, Masakazu, Nagaoka, Yoshiko, Chen, Irvin S. Y.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652112/
https://www.ncbi.nlm.nih.gov/pubmed/19300495
http://dx.doi.org/10.1371/journal.ppat.1000342