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SAP-controlled T-B cell interactions underlie germinal centre formation

Generation of long-term antibody-mediated immunity depends on the germinal centre (GC) reaction, which requires cooperation between antigen-specific T and B lymphocytes. In the human X-linked lymphoproliferative disease and its gene-targeted mouse model, loss-of-function mutations in signalling lymp...

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Detalles Bibliográficos
Autores principales: Qi, Hai, Cannons, Jennifer L., Klauschen, Frederick, Schwartzberg, Pamela L., Germain, Ronald N.
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652134/
https://www.ncbi.nlm.nih.gov/pubmed/18843362
http://dx.doi.org/10.1038/nature07345